Chlorhexidine Gluconate
- Basic Information
INCI Adopted Name: | Chlorhexidine digluconate |
CAS Registry No.: | 18472-51-0 |
EINECS No.: | 242-354-0 |
Molecular Formula: | C34H54Cl2N10O14 |
Molecular Weight: | 897.7572 |
Synonyms: | Chlorhexidine Gluconate |
- Physical and chemical properties
Chlorhexidine Gluconate is colorless to light yellow almost clarify and slightly sticky liquid, odorless.
Solubility: miscible with water, dissolved in ethanol or propanol.
- Specification
Item | Specification |
Character |
Colorless to light yellow almost clarify and slightly sticky liquid, odorless or almost odorless. |
The product is miscible with water, dissolved in ethanol or propanol. | |
Relative Density | Shall be 1.050~1.070 |
Identification | Item 1,2,3 shall be positive reaction |
Acidity | pH value is 5.5~7.0 |
P-chloroaniline | Should confirm the rule. |
Related Substance | Should confirm the rule ≤25ppm |
Residue on ignition | ≤0.1% |
Assay
Chlorhexidine Gluconate |
19.0%~21.0% (g/ml) |
- Application
Chlorhexidine Gluconate 20% Solution is a biguanide chlorobenzene with a wide range of antimicrobial activity. At pH 5.0 to 8.0, it is most effective against Gram-positive (10mcg/ml) and Gram-negative (50mcg/ml) bacteria.
Chlorhexidine Gluconate 20% Solution’s antibacterial and disinfectant effect is stronger than that of benzalkonium bromide and other disinfectants.
The antibacterial mechanism of Chlorhexidine Gluconate 20% Solution is mainly adsorbed on the osmotic barrier of the cell plasma membrane, which can cause the cell contents to leak out and exert antibacterial effects. It has an inhibitory effect at low concentrations, and has a bactericidal effect at high concentrations.
Chlorhexidine Gluconate 20% Solution mainly has antibacterial and disinfection effects. It can be used externally for hand and skin disinfection and washing wounds. It can be used as an antibacterial agent for surface wounds, skin cleansing agent, skin preparation before surgery, hand washing during surgery and hand washing agent for medical staff.
Chlorhexidine Gluconate 20% Solution has no obvious side effects, is mild, easy to clean, has no peculiar smell, does not pollute clothing, and is non-irritating to the skin.
Chlorhexidine Gluconate 20% Solution is a broad spectrum bacteriostatis antiseptic agent, oral care agent, disinfectant, cosmetic biocide, and preservative.
Chlorhexidine Gluconate 20% Solution is available over-the-counter in various formulations (e.g. solution, sponge, cloth, swab) as a topical antiseptic to sanitize prior to surgeries and/or medical procedures. Dental formulations, available by prescription only, include an oral rinse indicated for the treatment of gingivitis and a slow-release “chip” which is inserted into periodontal pockets and is indicated for the reduction of pocket depth in adult patients with periodontitis as an adjunct therapy to dental scaling and root planing procedures.
- Packing
25kg/ barrel or 200kg/barrel.
*Special requirements can be negotiated
- Storage
Avoid exposure to heat (104° F) and/or direct sunlight.
Ingredients: Chlorhexidine Gluconate
For External Use Only
Keep Out of Reach of Children
- Shelf life
24 months.