Chlorhexidine Gluconate

 

1. Basic Information

INCI Adopted Name:	Chlorhexidine digluconate
CAS Registry No.:	18472-51-0
EINECS No.:	242-354-0
Molecular Formula:	C34H54Cl2N10O14
Molecular Weight:	897.7572
Synonyms:	Chlorhexidine Gluconate

 

2. Physical and chemical properties

Chlorhexidine Gluconate is colorless to light yellow almost clarify and slightly sticky liquid, odorless.

Solubility: miscible with water, dissolved in ethanol or propanol.

 

3. Specification

Item	Specification
Character	Colorless to light yellow almost clarify and slightly sticky liquid, odorless or almost odorless.
	The product is miscible with water, dissolved in ethanol or propanol.
Relative Density	Shall be 1.050~1.070
Identification	Item 1,2,3 shall be positive reaction
Acidity	pH value is 5.5~7.0
P-chloroaniline	Should confirm the rule.
Related Substance	Should confirm the rule ≤25ppm
Residue on ignition	≤0.1%
Assay Chlorhexidine Gluconate	19.0%~21.0% （g/ml）

4. Application

Chlorhexidine Gluconate 20% Solution is a biguanide chlorobenzene with a wide range of antimicrobial activity. At pH 5.0 to 8.0, it is most effective against Gram-positive (10mcg/ml) and Gram-negative (50mcg/ml) bacteria.

Chlorhexidine Gluconate 20% Solution’s antibacterial and disinfectant effect is stronger than that of benzalkonium bromide and other disinfectants.

The antibacterial mechanism of Chlorhexidine Gluconate 20% Solution is mainly adsorbed on the osmotic barrier of the cell plasma membrane, which can cause the cell contents to leak out and exert antibacterial effects. It has an inhibitory effect at low concentrations, and has a bactericidal effect at high concentrations.

Chlorhexidine Gluconate 20% Solution mainly has antibacterial and disinfection effects. It can be used externally for hand and skin disinfection and washing wounds. It can be used as an antibacterial agent for surface wounds, skin cleansing agent, skin preparation before surgery, hand washing during surgery and hand washing agent for medical staff.

Chlorhexidine Gluconate 20% Solution has no obvious side effects, is mild, easy to clean, has no peculiar smell, does not pollute clothing, and is non-irritating to the skin.

Chlorhexidine Gluconate 20% Solution is a broad spectrum bacteriostatis antiseptic agent, oral care agent, disinfectant, cosmetic biocide, and preservative.

Chlorhexidine Gluconate 20% Solution is available over-the-counter in various formulations (e.g. solution, sponge, cloth, swab) as a topical antiseptic to sanitize prior to surgeries and/or medical procedures. Dental formulations, available by prescription only, include an oral rinse indicated for the treatment of gingivitis and a slow-release “chip” which is inserted into periodontal pockets and is indicated for the reduction of pocket depth in adult patients with periodontitis as an adjunct therapy to dental scaling and root planing procedures.

 

5. Packing

25kg/ barrel or 200kg/barrel.
*Special requirements can be negotiated

 

6. Storage

Avoid exposure to heat (104° F) and/or direct sunlight.

Ingredients: Chlorhexidine Gluconate

For External Use Only

Keep Out of Reach of Children

 

7. Shelf life

24 months.